ADAMTS13 Protein

An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in the ADAMTS13 gene have been identified in familial cases of PURPURA, THROMBOTIC THROMBOCYTOPENIC and defects in ADAMTS13 activity are associated with MYOCARDIAL INFARCTION; BRAIN ISCHEMIA; PRE-ECLAMPSIA; and MALARIA.

Also Known As:

A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 Protein; ADAMTS-13 Protein; ADAMTS13 Protease; vWF-Cleaving Protease; von Willebrand Factor-Cleaving Protease; ADAMTS 13 Protein; vWF Cleaving Protease; von Willebrand Factor Cleaving Protease

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Metalloproteases: 8276
        Metalloendopeptidases: 70
        ADAM Proteins: 24
        ADAMTS Proteins: 41
        ADAMTS13 Protein: 252
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - ADAMTS Proteins: 41
        ADAMTS13 Protein: 252
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - ADAMTS Proteins: 41
        ADAMTS13 Protein: 252
  - Scleroproteins: 74
    - Extracellular Matrix Proteins: 3148
      - ADAMTS Proteins: 41
        ADAMTS13 Protein: 252

K S Amankwah Selected Research

K S Amankwah Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure